Kesar (Saffron)

Powerful Antioxidant

Saffron contains an impressive variety of plant compounds that act as antioxidants — molecules that protect your cells against free radicals and oxidative stress. Notable saffron antioxidants include crocin, crocetin, safranal, and kaempferol. Crocin and crocetin are carotenoid pigments and responsible for saffron’s red color. Both compounds may have antidepressant properties, protect brain cells against progressive damage, improve inflammation, reduce appetite, and aid weight loss (2Trusted Source, 3Trusted Source).

Safranal gives saffron its distinct taste and aroma.

Research shows that it may help improve your mood, memory, and learning ability, as well as protect your brain cells against oxidative stress (4Trusted Source). Lastly, kaempferol is found in saffron flower petals. This compound has been linked to health benefits, such as reduced inflammation, anticancer properties, and antidepressant activity (2Trusted Source, 5Trusted Source).

2. May Improve Mood and Treat Depressive Symptoms

Saffron is nicknamed the “sunshine spice.”

That’s not just due to its distinct color, but also because it may help brighten your mood.

In a review of five studies, saffron supplements were significantly more effective than placebos at treating symptoms of mild-to-moderate depression.

Other studies found that taking 30 mg of saffron daily was just as effective as Fluoxetine, Imipramine, and Citalopram — conventional treatments for depression. Additionally, fewer people experienced side effects from saffron compared to other treatments (7Trusted Source, 8Trusted Source, 9Trusted Source).

What’s more, both the saffron petals and thread-like stigma appear to be effective against mild-to-moderate depression (1Trusted Source, 10Trusted Source).

While these findings are promising, longer human studies with more participants are needed before saffron can be recommended as a treatment for depression.

 

3. May Have Cancer-Fighting Properties

Saffron is high in antioxidants, which help neutralize harmful free radicals. Free radical damage has been linked to chronic diseases, such as cancer (11Trusted Source).

In test-tube studies, saffron and its compounds have been shown to selectively kill colon cancer cells or suppress their growth, while leaving normal cells unharmed (12Trusted Source).

This effect also applies to skin, bone marrow, prostate, lung, breast, cervix, and several other cancer cells (13Trusted Source).

What’s more, test-tube studies have found that crocin — the main antioxidant in saffron — may make cancer cells more sensitive to chemotherapy drugs (14Trusted Source).

While these findings from test-tube studies are promising, the anticancer effects of saffron are poorly studied in humans, and more research is needed.

4. May Reduce PMS Symptoms

Premenstrual syndrome (PMS) is a term that describes physical, emotional, and psychological symptoms occurring before the start of a menstrual period.

Studies show that saffron may help treat PMS symptoms.

In women 20–45 years of age, taking 30 mg of saffron daily was more effective than a placebo at treating PMS symptoms, such as irritability, headaches, cravings, and pain (15Trusted Source).

Another study found that simply smelling saffron for 20 minutes helped reduce PMS symptoms like anxiety and lowered levels of the stress hormone cortisol (16Trusted Source).